Comparison of several confidence intervals for QTL location

  title={Comparison of several confidence intervals for QTL location},
  author={Brigitte Mangin and Bruno Goffinet},
The confidence interval for the map location of quantitative trait loci (QTL) is a very important quantity for geneticists. The one LOD support interval has been proved to be a biased confidence interval. Moreover the distribution of the LOD score has been shown to depend on the value of the QTL effect, which is why the LOD score cannot be used to build an unbiased confidence interval when the value of the QTL effect is unknown. A new confidence interval based on a maximun likelihood ratio test… CONTINUE READING
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