Comparison of sequence masking algorithms and the detection of biased protein sequence regions

@article{Kreil2003ComparisonOS,
  title={Comparison of sequence masking algorithms and the detection of biased protein sequence regions},
  author={David P. Kreil and Christos A. Ouzounis},
  journal={Bioinformatics},
  year={2003},
  volume={19 13},
  pages={
          1672-81
        }
}
MOTIVATION Separation of protein sequence regions according to their local information complexity and subsequent masking of low complexity regions has greatly enhanced the reliability of function prediction by sequence similarity. Comparisons with alternative methods that focus on compositional sequence bias rather than information complexity measures have shown that removal of compositional bias yields at least as sensitive and much more specific results. Besides the application of sequence… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 47 REFERENCES

Different types of repeat expansion in the TATAbinding protein gene are associated with a new form of inherited ataxia

  • O. Riess, C. Klein, E. Schwinger
  • Eur . J . Hum . Genet .
  • 2001