Comparison of saruplase and alteplase in acute myocardial infarction. SESAM Study Group. The Study in Europe with Saruplase and Alteplase in Myocardial Infarction.

@article{Br1997ComparisonOS,
  title={Comparison of saruplase and alteplase in acute myocardial infarction. SESAM Study Group. The Study in Europe with Saruplase and Alteplase in Myocardial Infarction.},
  author={Frits W. H. M. B{\"a}r and Juergen Meyer and Frank Vermeer and Rolf H Michels and Bernard Charbonnier and Klaus Haerten and Martin Spiecker and Carlos M Macaya and Michel Hanssen and Magdalena Heras and James Boland and Marie Claude Morice and Francis Gerard Dunn and Rainer Uebis and C. W. Hamm and Oded Ayzenberg and Gerhard Strupp and Adrie J A M Withagen and Werner Klein and J. Windeler and Gwyn R. Hopkins and Hannes Barth and M J von Fisenne},
  journal={The American journal of cardiology},
  year={1997},
  volume={79 6},
  pages={727-32}
}
Four hundred seventy-three patients with acute myocardial infarction (AMI) were treated with either saruplase (80 mg/hour, n = 236) or alteplase (100 mg every 3 hours, n = 237). Comedication included heparin and acetylsalicylic acid. Angiography was performed at 45 and 60 minutes after the start of thrombolytic therapy. When flow was insufficient, angiography was repeated at 90 minutes. Coronary angioplasty was then performed if Thrombolysis In Myocardial Infarction (TIMI) trial 0 to 1 flow was… CONTINUE READING

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