Comparison of retinal nerve-fiber layer in high- and normal-tension glaucoma

@article{Yamazaki2004ComparisonOR,
  title={Comparison of retinal nerve-fiber layer in high- and normal-tension glaucoma},
  author={Y. Yamazaki and C. Koide and T. Miyazawa and Nobuo Kuwagaki and H. Yamada},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2004},
  volume={229},
  pages={517-520}
}
AbstractIn all, 20 eyes of 20 normal-tension glaucoma (NTG) patients and 20 eyes of high-tension glaucoma (HTG) patients matched for similar visual field defects underwent retinal nerve-fiber-layer (RNFL) analysis using a computerized digital-image analysis system. Subjects with NTG showed more localized RNFL loss than diffuse loss as compared with HTG patients. The results support the hypothesis that there may be different mechanisms of damage in glaucoma. Offprint requests to: Y. Yamazaki 
Diffuse nerve fiber layer loss in normal tension glaucoma
TLDR
The result suggests that, even in NTG, IOP may be an important factor causing optic nerve damage, and that retinal nerve fiber layer loss in the RNFL area corresponded to the spared visual hemifield as compared to those with the maximum IOP<19 mmHg. Expand
Retinal Nerve Fiber Layer Measures in High- and Normal-Tension Glaucoma
TLDR
There is no difference in the spatial pattern of RNFL defects, as assessed by the OCT, between HTG and NTG and to predict diffuse and localized RNFL loss as a function of age, mean defect, spherical equivalent, disease group, and location. Expand
Pattern of retinal nerve fiber layer damage in Korean eyes with normal-tension glaucoma and hemifield visual field defect
TLDR
Despite strict selection of the eyes with visual field defect confined to one hemifield, a mixture of both focal and diffuse RNFL damage was noted, with a common occurrence of symmetrical RNFL thinning in both upper and lower quadrants based on scanning laser polarimetry. Expand
Comparison of Retinal Nerve Fiber Layer Thickness in Early Normal-Tension Glaucoma and Early Primary Open-Angle Glaucoma
TLDR
All R NFL thickness values except for the temporal quadrant RNFL thickness were significantly decreased in the early NTG and POAG groups, and the area under the receiver operating characteristics curve (AUROC) was determined for the detection of early glaucoma. Expand
Optical coherence tomography in the evaluation of structural changes in primary open-angle glaucoma with and without elevated intraocular pressure.
TLDR
OCT measurements of the RNFL thickness provide clinically significant information in monitoring of glaucomatous changes and there are no differences in the patterns of RNFL defects per sectors and quadrants between NTG and HTG, measured by OCT. Expand
Patterns of Retinal Nerve Fiber Layer Loss in Different Subtypes of Open Angle Glaucoma Using Spectral Domain Optical Coherence Tomography
TLDR
Of the 4 OAG subtypes, PXG patients exhibited the greatest degree of inter-eye RNFL asymmetry, suggesting that SD-OCT may be able to detect significant differences in patterns of RNFL thinning for different subtypes of OAG. Expand
Variations in optic nerve head morphology by intraocular pressure in open-angle glaucoma
TLDR
Normal-tension and high-Tension glaucoma are not distinguishable by optic nerve head topography with HRT and OCT when the degree of damage by Humphrey visual field testing is taken into account. Expand
Comparison of Macular Ganglion Cell Complex Thickness by Fourier-Domain OCT in Normal Tension Glaucoma and Primary Open-Angle Glaucoma
TLDR
Perimacular GCC parameters could be a good alternative or supplement to peripapillary RNFL measurements for diagnosis and research in patients with NTG and primary open-angle glaucoma. Expand
Macular Inner Plexiform and Retinal Nerve Fiber Layer Thickness in Glaucoma
TLDR
The diagnostic ability of the mGCIPL thickness was comparable to that of the pRNFL thickness in patients with NTG or POAG, and the superior, superotemporal, and superonasal thickness of m GCIPL and the inferior thickness of pR NFL showed significant reductions and significantly higher AROCs for distinguishing between normal eyes and eyes with glaucoma in POAG compared with those in NTG. Expand
Comparisons of ganglion cell-inner plexiform layer loss patterns and its diagnostic performance between normal tension glaucoma and primary open angle glaucoma: a detailed, severity-based study.
TLDR
The minimum GCIPL thickness has the best diagnostic performance in differentiating NTG or POAG from normal subjects, which is comparable to that of the average and inferior RNFL thickness. Expand
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