Comparison of response to a selective serotonin reuptake inhibitor in children, adolescents, and adults with posttraumatic stress disorder.

@article{Seedat2002ComparisonOR,
  title={Comparison of response to a selective serotonin reuptake inhibitor in children, adolescents, and adults with posttraumatic stress disorder.},
  author={Soraya Seedat and D. J. Stein and Carl F Ziervogel and Tessa Middleton and Deborah Kaminer and Robin Emsley and Wendy Rossouw},
  journal={Journal of child and adolescent psychopharmacology},
  year={2002},
  volume={12 1},
  pages={37-46}
}
BACKGROUND Although the pathophysiology of posttraumatic stress disorder (PTSD) is considered multifactorial, empirical evidence suggests that serotonergic dysregulation may characterize the disorder. The efficacy of the selective serotonin reuptake inhibitors (SSRIs) in treating essential symptoms (re-experiencing, avoidance, numbing, hyperarousal) in both adults and children is likely to involve potentiation of this neurotransmitter. OBJECTIVE This study compared outcome in an 8-week open… CONTINUE READING

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