Comparison of respiratory responses to Metarhizium anisopliae extract using two different sensitization protocols.

@article{Ward2000ComparisonOR,
  title={Comparison of respiratory responses to Metarhizium anisopliae extract using two different sensitization protocols.},
  author={Marsha D. W. Ward and Suzanne Michelle Madison and Debora L. Andrews and Denise M. Sailstad and Stephen H Gavett and Mary Jane K. Selgrade},
  journal={Toxicology},
  year={2000},
  volume={147 2},
  pages={
          133-45
        }
}
Metarhizium anisopliae, an entomopathogenic fungus, is a prototypic microbial pesticide licensed for indoor control of cockroaches, a major source of allergens. We have previously demonstrated allergy and asthma-like responses in BALB/c mice intraperitoneally (IP) sensitized in the presence of adjuvant and intratracheally (IT) challenged with the soluble factors from M. anisopliae crude antigen (MACA) (Ward et al., 1998, 2000). This protocol has been used frequently to establish animal models… CONTINUE READING
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