Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays.

Abstract

Human diploid fibroblasts (HDFs) exposed to subcytotoxic stress display many features of senescence. Using differential display RT-PCR, gene expression of HDFs in premature senescence induced by tert-butylhydroperoxide or ethanol and in replicative senescence was compared to gene expression of HDFs at early cumulative population doublings. Thirty genes of… (More)

Topics

Cite this paper

@article{Pascal2005ComparisonOR, title={Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays.}, author={Thierry G. Pascal and Florence Debacq-Chainiaux and Aline Chr{\'e}tien and Coralie Bastin and Anne-France Dab{\'e}e and Vincent Bertholet and Jos{\'e} Remacle and Olivier Toussaint}, journal={FEBS letters}, year={2005}, volume={579 17}, pages={3651-9} }