Comparison of reduced-intensity and myeloablative conditioning regimens for allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia and acute lymphoblastic leukemia: a meta-analysis.

@article{Wahid2014ComparisonOR,
  title={Comparison of reduced-intensity and myeloablative conditioning regimens for allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia and acute lymphoblastic leukemia: a meta-analysis.},
  author={S Fadilah S Abdul Wahid and Nor-Azimah Ismail and Mohd-Razif Mohd-Idris and Fariza Wan Jamaluddin and NorRafeah Tumian and Ernie Yap Sze-Wei and Norasiah Muhammad and Ming Lai Nai},
  journal={Stem cells and development},
  year={2014},
  volume={23 21},
  pages={
          2535-52
        }
}
Currently, the indications to perform reduced-intensity conditioning allogeneic hematopoietic stem cell transplant (RIC-HCT) are based on data derived mainly from large registry and single-centre retrospective studies. Thus, at the present time, there is limited direct evidence supporting the current practice in selecting patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) for RIC versus myeloablative conditioning (MAC) transplants. To determine the relationship… CONTINUE READING
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