Comparison of radio-iodinated serum albumin and blue dextran as indicators to measure rate of formation of cerebrospinal fluid

@article{Martins1975ComparisonOR,
  title={Comparison of radio-iodinated serum albumin and blue dextran as indicators to measure rate of formation of cerebrospinal fluid},
  author={A. Martins and A. Ramirez and T. Doyle},
  journal={Experimental Neurology},
  year={1975},
  volume={47},
  pages={249-256}
}
Abstract The characteristics of two nondiffusible indicators, 125I-labeled albumin (RISA-125) and blue dextran, were compared by using them simultaneously to measure rate of formation of cerebrospinal fluid (CSF) in in vitro experiments and in a series of ventriculocisternal perfusion experiments in rhesus monkeys. Mean CSF formation calculated from the dilution of RISA-125 was 37.6 μl/min (±0.74 sem ); the CSF formation calculated from the corresponding dilution of blue dextran was 37.1 μl/min… 
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The choroid plexus, a major source of CSF, is demonstrated to be less reactive to vasodilatation induced by either hypercapnia or a vasoactive agent, and favorably explanes, at least partially, the unchanged Vf under the effect of hyper capnia or papaverine.
ventriculocisternal perfusion . cerebrospinal fluid formation by Sources of error in measuring
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TLDR
The results suggest that lung liquid production requires glycolysis and aerobic metabolism, however, reabsorption appears to continue on gly colysis alone, a particularly useful situation for neonates suffering respiratory distress.
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Cerebrospinal fluid (CSF) was removed continuously in 2- or 3-h aliquots from the lateral and fourth cerebral ventricles of chronic chair restrained rhesus monkeys. Under conditions of 12 h light
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