Comparison of racecadotril and loperamide in adults with acute diarrhoea.

@article{Vetel1999ComparisonOR,
  title={Comparison of racecadotril and loperamide in adults with acute diarrhoea.},
  author={J M Vetel and Henri B{\'e}rard and N Fretault and J. M. Lecomte},
  journal={Alimentary pharmacology & therapeutics},
  year={1999},
  volume={13 Suppl 6},
  pages={21-6}
}
METHODS A multicentre, randomized, double-blind, double-placebo, parallel-group study was carried out to compare the efficacy, tolerability, and safety of racecadotril (100 mg three times daily) and loperamide (2 mg after each diarrhoeic stool) in 157 adults with acute diarrhoea. Patients were treated for 7 days or until recovery, if this took place earlier. RESULTS Both groups of patients passed similar numbers (mean +/- S.E.M.) of stools before recovery (3.5 +/- 0.5 for racecadotril vs. 2.9… CONTINUE READING

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