Comparison of quantitative high performance thin layer chromatography and the high performance liquid chromatography of parabens.

@article{Thomassin1997ComparisonOQ,
  title={Comparison of quantitative high performance thin layer chromatography and the high performance liquid chromatography of parabens.},
  author={Mireille Thomassin and Eric Cavalli and Y Guillaume and Christiane Guinchard},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={1997},
  volume={15 6},
  pages={831-8}
}
A method is described for the densitometric determination of the p-hydroxybenzoic esters and p-hydroxybenzoic acid in mixtures or in drugs. This method is compared with the one used in high performance liquid chromatography (HPLC). The calibration curves were linear in interval 0.250-3.60 mumol ml-1 per 200 nl per spot. The limit of detection and the relative standard deviation (RSD) are higher than in HPLC (RSD is 6% in HPTLC. 3% in HPLC; limit of detection about 40 pmol in HPTLC and 25 pmol… CONTINUE READING

Similar Papers

Loading similar papers…