Comparison of protein oxidation and aldehyde formation during oxidative stress in isolated mitochondria.

@article{Reinheckel1998ComparisonOP,
  title={Comparison of protein oxidation and aldehyde formation during oxidative stress in isolated mitochondria.},
  author={Thomas Reinheckel and Heiko Noack and Stefan Lorenz and Ingrid Wiswedel and Wolfgang Augustin},
  journal={Free radical research},
  year={1998},
  volume={29 4},
  pages={297-305}
}
Oxidative stress is known to cause oxidative protein modification and the generation of reactive aldehydes derived from lipid peroxidation. Extent and kinetics of both processes were investigated during oxidative damage of isolated rat liver mitochondria treated with iron/ascorbate. The monofunctional aldehydes 4-hydroxynonenal (4-HNE), n-hexanal, n… CONTINUE READING