Comparison of protein enrichment strategies for proteome analysis of plasma.

Abstract

Efforts to discover protein biomarkers in plasma are hampered by the high abundance of few proteins, which interfere with the detection of low-abundant proteins. Different commercially available protein-partitioning products were tested for their ability to lower the detection limit of proteins in 2-D gels. Immuno-depletion using polyclonal antibodies… (More)
DOI: 10.1002/pmic.200900431

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