Comparison of protective effects of trimetazidine against experimental warm ischemia of different durations: early and long-term effects in a pig kidney model.

@article{Jayle2007ComparisonOP,
  title={Comparison of protective effects of trimetazidine against experimental warm ischemia of different durations: early and long-term effects in a pig kidney model.},
  author={Christophe P. M. Jayle and Fr{\'e}d{\'e}ric Favreau and Kequiang Zhang and Carole Doucet and Jean Michel Goujon and William H{\'e}brard and Michel Carretier and Michel Eugene and G{\'e}rard Mauco and Jean Paul Tillement and Thierry Hauet},
  journal={American journal of physiology. Renal physiology},
  year={2007},
  volume={292 3},
  pages={F1082-93}
}
Acute renal failure (ARF) is often the consequence of an ischemia-reperfusion injury (IRI) and associated with high mortality. Warm ischemia (WI) is a crucial factor of tissue damage, and tissue destruction led by ischemia-reperfusion (I/R) can impact the early and long-term functional outcome. Trimetazidine (TMZ) is an anti-ischemic drug. Previously, we already verified its protective effect on a cold-ischemic pig kidney model by directly adding TMZ into the preservation solution (Faure JP… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 45 references

Effect of trimetazidine on the nucleotide profile in rat kidney with ischemia-reperfusion injury

  • L Domanski, T Sulikowski, +5 authors K. Ciechanowski
  • Eur J Pharm Sci
  • 2006
1 Excerpt

Similar Papers

Loading similar papers…