Comparison of protection afforded by whole virus ISCOM versus MDP adjuvanted formalin-inactivated SIV vaccines from IV cell-free or cell-associated homologous challenge.

Abstract

A SIV-ISCOM and a SIV-MDP adjuvanted vaccine were tested for their potential to induce protection from intravenous cell-free or cell-associated homologous SIV challenge in rhesus monkeys (Macaca mulatta). Seven monkeys vaccinated four times over a four-month period with either the SIV-ISCOM or the SIV-MDP vaccine were challenged intravenously with… (More)

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@article{Osterhaus1992ComparisonOP, title={Comparison of protection afforded by whole virus ISCOM versus MDP adjuvanted formalin-inactivated SIV vaccines from IV cell-free or cell-associated homologous challenge.}, author={Albert Osterhaus and Peter M. J. M. De Vries and Bror Morein and Leif {\AA}kerblom and John Heeney}, journal={AIDS research and human retroviruses}, year={1992}, volume={8 8}, pages={1507-10} }