Comparison of poloxamer- and chitosan-based thermally sensitive gels for the treatment of vaginal mucositis.

@article{Rossi2014ComparisonOP,
  title={Comparison of poloxamer- and chitosan-based thermally sensitive gels for the treatment of vaginal mucositis.},
  author={Silvia Rossi and Franca Ferrari and Maria Cristina Bonferoni and Giuseppina Sandri and Angela Faccendini and Antonella Puccio and Carla Marcella Caramella},
  journal={Drug development and industrial pharmacy},
  year={2014},
  volume={40 3},
  pages={
          352-60
        }
}
CONTEXT The local treatment of vaginal mucositis requires an intimate and prolonged contact of anti-infective drugs with the mucosa. This can be achieved by means of mucoadhesive and thermally sensitive vehicles, capable of gelifying at the physiological temperature. OBJECTIVE The aim of the present work was to compare the potentiality of poloxamer 407 (PLX)/chitosan lactate (CS-L) and CS-L/glycerophosphate (GP) mixtures as mucoadhesive thermally sensitive vehicles for the treatment of… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

A CCR5 antagonist-based HIV entry inhibitor exhibited potent spermicidal activity: Potential application for contraception and prevention of HIV sexual transmission.

  • European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
  • 2018
VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 36 REFERENCES

Enhancing and sustaining the topical ocular delivery of fluconazole using chitosan solution and poloxamer/chitosan in situ forming gel.

  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2011
VIEW 2 EXCERPTS

Formulation of mucoadhesive vaginal hydrogels insensitive to dilution with vaginal fluids.

  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2010

Thermally sensitive gels based on chitosan derivatives for the treatment of oral mucositis.

  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2010

A novel poloxamers/hyaluronic acid in situ forming hydrogel for drug delivery: rheological, mucoadhesive and in vitro release properties.

  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2008