Comparison of platelet production in two strains of mice with different modal megakaryocyte DNA ploidies after exposure to hypoxia.

Abstract

Thrombocytopenia develops with prolonged exposure to hypoxia. Although decreases in megakaryocyte numbers due to hypoxia have been well documented, the effects of hypoxia on megakaryocyte DNA content have not been reported. In this study, megakaryocytopoiesis and platelet production were compared in both C3H mice (whose megakaryocyte modal ploidy class is… (More)

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@article{McDonald1992ComparisonOP, title={Comparison of platelet production in two strains of mice with different modal megakaryocyte DNA ploidies after exposure to hypoxia.}, author={Tyson McDonald and Marie Cottrell and Shirley A. Steward and Raymond E. Clift and Christopher J. Swearingen and Carl W. Jackson}, journal={Experimental hematology}, year={1992}, volume={20 1}, pages={51-6} }