Comparison of phenotype expression by mononuclear phagocytes within subcutaneous gouty tophi and rheumatoid nodules

@article{Palmer1987ComparisonOP,
  title={Comparison of phenotype expression by mononuclear phagocytes within subcutaneous gouty tophi and rheumatoid nodules},
  author={David Gordon Palmer and Nancy Hogg and Ian Denholm and C A Allen and John Highton and Paul A Hessian},
  journal={Rheumatology International},
  year={1987},
  volume={7},
  pages={187-193}
}
SummaryThe mononuclear phagocyte infiltrate which occupies the gout tophus has been compared with that of the subcutaneous rheumatoid nodule. In the gout tophus, macrophage migration appears to be at a relatively low level and effectively terminates once these cells have been recruited into the corona. In the nodule the evidence suggests that both macrophage and granulocyte populations continuously migrate towards, and are progressively incorporated into, the necrotic centres. These… CONTINUE READING

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