Comparison of paroxetine and nortriptyline in depressed patients with ischemic heart disease.

@article{Roose1998ComparisonOP,
  title={Comparison of paroxetine and nortriptyline in depressed patients with ischemic heart disease.},
  author={S P Steven P Roose and Fouzia Laghrissi-Thode and John S Kennedy and Jennifer C. Nelson and J. Thomas Bigger and Bruce G. Pollock and Andrew Gaffney and Mallika Narayan and Mitchell S. Finkel and James McCafferty and Ivan Gergel},
  journal={JAMA},
  year={1998},
  volume={279 4},
  pages={287-91}
}
CONTEXT Depression and ischemic heart disease often are comorbid conditions and, in patients who have had a myocardial infarction, the presence of depression is associated with increased mortality. Patients with heart disease need a safe and effective treatment for depression. OBJECTIVE To compare the efficacy, cardiovascular effects, and safety of a specific serotonin reuptake inhibitor, paroxetine, with a tricyclic antidepressant, nortriptyline hydrochloride, in depressed patients with… CONTINUE READING
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