Comparison of ordinary, weighted, and generalized least-squares straight-line calibrations for LC-MS-MS, GC-MS, HPLC, GC, and enzymatic assay.

Abstract

The impact of experimental errors in one or both variables on the use of linear least-squares was investigated for method calibrations (response = intercept plus slope times concentration, or equivalently, Y = a(1) + a(2)X ) frequently used in analytical toxicology. In principle, the most reliable calibrations should consider errors from all sources, but… (More)

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Cite this paper

@article{Duer2008ComparisonOO, title={Comparison of ordinary, weighted, and generalized least-squares straight-line calibrations for LC-MS-MS, GC-MS, HPLC, GC, and enzymatic assay.}, author={Wayne C Duer and Paul J Ogren and Alison Meetze and Chester J Kitchen and Ryan Von Lindern and Dustin C Yaworsky and Christopher D. J. Boden and Jeffery A Gayer}, journal={Journal of analytical toxicology}, year={2008}, volume={32 5}, pages={329-38} }