Comparison of opioid agonists in maintaining responding and in suppressing morphine withdrawal in rhesus monkeys

@article{Young1981ComparisonOO,
  title={Comparison of opioid agonists in maintaining responding and in suppressing morphine withdrawal in rhesus monkeys},
  author={Alice M. Young and Henry H. Swain and J. H. Woods},
  journal={Psychopharmacology},
  year={1981},
  volume={74},
  pages={329-335}
}
Sixteen opioid agonists were studied for their capacity both to maintain responding previously reinforced by codeine and to suppress the withdrawal syndrome induced by morphine deprivation in rhesus monkeys. All compounds, which included examples from each of the major chemical families of opioids, maintained responding at rates above those maintained by saline. There were differences among the compounds in the maximal response rates maintained, and large differences in their potencies in… CONTINUE READING

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