Comparison of on-chip and off-chip microfluidic kinase assay formats.

@article{Dunne2004ComparisonOO,
  title={Comparison of on-chip and off-chip microfluidic kinase assay formats.},
  author={Jude Dunne and Holly T. Reardon and Vy Trinh and Ella Li and Javier Farinas},
  journal={Assay and drug development technologies},
  year={2004},
  volume={2 2},
  pages={121-9}
}
Kinases represent an important class of targets for pharmaceutical drug development. Microfluidic devices capable of running kinase assays with either an on-chip or an off-chip enzymatic reaction have been developed. For the on-chip assay, reagent addition, mixing, enzymatic reaction, and electrophoretic separation and detection of substrate and product all… CONTINUE READING