Comparison of multiple methods for identification of hyperprolactinemia in the presence of macroprolactin.

@article{McCudden2010ComparisonOM,
  title={Comparison of multiple methods for identification of hyperprolactinemia in the presence of macroprolactin.},
  author={Christopher R. McCudden and Julie L. Sharpless and David G. Grenache},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2010},
  volume={411 3-4},
  pages={155-60}
}
BACKGROUND Macroprolactin is a large, heterogeneous form of prolactin with limited bioavailability. Detection of macroprolactin by different immunoassays varies widely. The objectives of this study were to determine the immunoreactivity of macroprolactin by the Ortho Clinical Diagnostics Vitros((R)) ECi prolactin immunoassay, establish the most effective method for interpreting the prolactin concentration after PEG-precipitation, and correlate the clinical features of hyperprolactinemia with… CONTINUE READING

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