Comparison of multiple assays for kinetic detection of apoptosis in thymocytes exposed to dexamethasone or diethylstilbesterol.

@article{Donner1999ComparisonOM,
  title={Comparison of multiple assays for kinetic detection of apoptosis in thymocytes exposed to dexamethasone or diethylstilbesterol.},
  author={Karl Johan Donner and Kenneth M. Becker and Bruce D. Hissong and Sattar Ansar Ahmed},
  journal={Cytometry},
  year={1999},
  volume={35 1},
  pages={80-90}
}
BACKGROUND Techniques to measure apoptosis are used to study a wide spectrum of conditions, from acquired immune deficiency syndrome (AIDS) to cancer to autoimmune diseases. Therefore, a critical comparison of common assays for apoptosis is warranted. METHODS The kinetics of apoptosis induction in dexamethasone (DEX)-exposed thymocytes was examined after 2, 4, 8, 12, 26-28, and 48-50 h of culture. An additional aim was to ascertain whether a similar thymic atrophy-inducing hormone… CONTINUE READING