Comparison of morpholino based translational inhibition during the development of Xenopus laevis and Xenopus tropicalis

@article{Nutt2001ComparisonOM,
  title={Comparison of morpholino based translational inhibition during the development of Xenopus laevis and Xenopus tropicalis},
  author={S. Nutt and O. Bronchain and K. Hartley and E. Amaya},
  journal={genesis},
  year={2001},
  volume={30}
}
Summary: Morpholino (MO) based inhibition of translational initiation represents an attractive methodology to eliminate gene function during Xenopus development (Heasman et al., 2000). However, the degree to which a given target protein can be eliminated and the longevity of this effect during embryogenesis has not been documented. To examine the efficacy of MOs, we have used transgenic Xenopus lines that harbour known numbers of integrations of a GFP reporter under the control of the… Expand
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