Comparison of mobile-phase systems commonly applied in liquid chromatography-mass spectrometry of nucleic acids.

Abstract

LC-MS represents an important technology for the qualitative and quantitative analysis of nucleic acids. For MS, ESI in negative ion mode is used. The chromatographic method of choice is ion-pair (IP) RP chromatography. Chromatographic separations are usually accomplished by gradients of an organic modifier in aqueous solutions of IP reagents. Commonly… (More)
DOI: 10.1002/elps.201300269

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@article{Erb2014ComparisonOM, title={Comparison of mobile-phase systems commonly applied in liquid chromatography-mass spectrometry of nucleic acids.}, author={Robert Erb and Herbert Oberacher}, journal={Electrophoresis}, year={2014}, volume={35 9}, pages={1226-35} }