Comparison of methods for identifying resistant herpes simplex virus and measuring antiviral susceptibility.


BACKGROUND A number of in vitro assays are used to determine susceptibility of HSV to antiviral agents, but results from these in vitro assays do not necessarily correlate with treatment outcome. OBJECTIVES A method with improved capability for identifying an isolate as acyclovir (ACV) or penciclovir (PCV) resistant when resistance is borderline could… (More)


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