Comparison of mesenchymal stem cells derived from fat, bone marrow, Wharton's jelly, and umbilical cord blood for treating spinal cord injuries in dogs.

@article{Ryu2012ComparisonOM,
  title={Comparison of mesenchymal stem cells derived from fat, bone marrow, Wharton's jelly, and umbilical cord blood for treating spinal cord injuries in dogs.},
  author={Hak-Hyun Ryu and Byung-Jae Kang and Sung-Su Park and Yongsun Kim and Gyu-Jin Sung and H M Woo and Wan Hee Kim and Oh-Kyeong Kweon},
  journal={The Journal of veterinary medical science},
  year={2012},
  volume={74 12},
  pages={1617-30}
}
Previous animal studies have shown that transplantation of mesenchymal stem cells (MSCs) into spinal cord lesions enhances axonal regeneration and promotes functional recovery. We isolated the MSCs derived from fat, bone marrow, Wharton's jelly and umbilical cord blood (UCB) positive for MSC markers and negative for hematopoietic cell markers. Their effects on the regeneration of injured canine spinal cords were compared. Spinal cord injury was induced by balloon catheter compression. Dogs with… CONTINUE READING