Comparison of membrane fluidity and transferrin receptor expression as proliferation markers in lymphoproliferative disorders and in mitogen induced lymphoblasts.

The correlation of two proliferation related events, membrane fluidization and transferrin receptor expression was studied in different lymphoid cells. With increasing grade of malignancy the membrane microviscosity decreased. Moreover, resting lymphocytes differed significantly from chronic lymphocytic leukaemia cells in this parameter. [125I]Fe2… CONTINUE READING