Comparison of liver regeneration after a splenectomy and splenic artery ligation in a dimethylnitrosamine-induced cirrhotic rat model.

@article{Morinaga2010ComparisonOL,
  title={Comparison of liver regeneration after a splenectomy and splenic artery ligation in a dimethylnitrosamine-induced cirrhotic rat model.},
  author={Akio Morinaga and T. Ogata and Masayosi Kage and H. Kinoshita and S. Aoyagi},
  journal={HPB : the official journal of the International Hepato Pancreato Biliary Association},
  year={2010},
  volume={12 1},
  pages={
          22-30
        }
}
  • Akio Morinaga, T. Ogata, +2 authors S. Aoyagi
  • Published 2010
  • Medicine
  • HPB : the official journal of the International Hepato Pancreato Biliary Association
AIM A splenectomy and splenic artery ligation accelerate liver regeneration and improve liver function after a hepatectomy. However, there are no studies that directly compared the effects of a splenectomy and splenic artery ligation. In the present study, we compared the effects of a splenectomy and splenic artery ligation in cirrhotic rats. METHODS Dimethylnitrosamine (DMN) was administered intraperitoneally for 4 weeks to induce cirrhosis. The rats were divided into three groups: sham… Expand
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