Comparison of line‐field confocal optical coherence tomography images with histological sections: Validation of a new method for in vivo and non‐invasive quantification of superficial dermis thickness

@article{Pedrazzani2019ComparisonOL,
  title={Comparison of line‐field confocal optical coherence tomography images with histological sections: Validation of a new method for in vivo and non‐invasive quantification of superficial dermis thickness},
  author={M{\'e}lanie Pedrazzani and Josselin Breugnot and Pauline Rouaud-Tinguely and Maxime Cazalas and Arthur J. Davis and Sylvie Bordes and Arnaud Dubois and Brigitte Closs},
  journal={Skin Research and Technology},
  year={2019},
  volume={26},
  pages={398 - 404}
}
Line‐field confocal optical coherence tomography (LC‐OCT) is an imaging technique providing “optical biopsies” of the skin in real time and non‐invasively. At a center optical wavelength of 1.3 µm, this innovative technology can be applied to dermo‐cosmetic product development due to both high image resolution (~2 µm) and sufficient penetration (~0.5 mm). Nevertheless, the precise dermal area analyzed with LC‐OCT has never been identified. In this study, the objective was to compare LC‐OCT… Expand
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