Comparison of learning‐related neuronal activity in the dorsal premotor cortex and striatum

  title={Comparison of learning‐related neuronal activity in the dorsal premotor cortex and striatum},
  author={Peter J. Brasted and Steven P. Wise},
  journal={European Journal of Neuroscience},
Previous studies have reported learning‐related changes in neuronal activity during conditional visuomotor learning, also known as arbitrary sensorimotor mapping, conditional visual discrimination, and symbolic or endogenous mapping. Qualitatively similar observations have been reported for the dorsal premotor cortex, the supplementary eye field, the prefrontal cortex, the hippocampus, the striatum and the globus pallidus. The fact that cells in both the dorsal premotor cortex (PMd) and the… 

Different time courses of learning-related activity in the prefrontal cortex and striatum

During associative learning in monkeys, neural activity in these areas changes at different rates: the striatum showed rapid, almost bistable, changes compared with a slower trend in the prefrontal cortex that was more in accordance with slow improvements in behavioural performance.

Cortico‐basal ganglia pathways are essential for the recall of well–established visuomotor associations

It is suggested that when visuomotor associations have become well established through over‐training, performance depends on connections between the basal ganglia and premotor cortex.

Comparison of associative learning-related signals in the macaque perirhinal cortex and hippocampus.

It is reported that a population of perirhinal neurons signal newly learned associations by changing their firing rate correlated with the animal's behavioral learning curve, and suggested that the perirHinal cortex together with the hippocampus contribute importantly to conditional-motor associative memory formation.

On a basal ganglia role in learning and rehearsing visual–motor associations

Striatal and medial temporal lobe functional interactions during visuomotor associative learning.

Findings suggest dissociable computational roles for different subregions of the striatum and MTL interact in distinct ways, perhaps forming functionally integrated networks during the learning of arbitrary associations.

Integrating associative learning signals across the brain

The patterns of learning‐related activity seen in motor‐related areas throughout the frontal lobe and striatum during conditional motor learning are reviewed to provide insight into the unique contribution of each area to associative learning.

Conditional visuo-motor learning and dimension reduction

A mathematical model inspired by viability theory developed to implement the use of strategies during learning is presented, which complements existing models of the BG based on reinforcement learning (RL), which do not take into account theUse of strategies to reduce the dimension of the learning space.

Comparison of population activity in the dorsal premotor cortex and putamen during the learning of arbitrary visuomotor mappings

It is reported that, in both regions, the population activity for novel mappings came to resemble that for familiar ones as learning progressed, supporting the hypothesis that neurons in the striatum play a pivotal role in associative learning.

Cortico-basal ganglia networks subserving goal-directed behavior mediated by conditional visuo-goal association

  • E. Hoshi
  • Psychology, Biology
    Front. Neural Circuits
  • 2013
Neuronal activity recorded from the four key areas of the brains of monkeys performing a task involving conditional visuo-goal association revealed three major mechanisms underlying this process, including visual-object signals are represented primarily in the vlPFC and BG, and all four areas are involved in initially determining the goals based on the visual signals.



Neuronal activity in the monkey striatum during conditional visuomotor learning

The findings suggest that the striatum is involved in early stages of conditional visuomotor learning, and are interpreted in relation with previous data on frontal cortex.

Experience-Dependent Activation Patterns in Human Brain during Visual-Motor Associative Learning

The current results provide a foundation for understanding how neocortical structures participate in the various behavioral processes that combine to form and consolidate novel and arbitrary sensory-motor associations.

Changes of cortico-striatal effective connectivity during visuomotor learning.

It is inferred that novel visuomotor associations are established through the enhancement of specific cortico-striatal circuits, rather than through the alteration of direct temporo-frontal or parieto- frontal connectivity.

Learning-dependent neuronal activity in the premotor cortex: activity during the acquisition of conditional motor associations

  • AR MitzM. GodschalkS. Wise
  • Biology, Psychology
    The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1991
The present findings support a role for premotor cortex in motor preparation, generally, and suggest a specific role in the selection of movements on the basis of arbitrary associations.

Convergent Inputs from Thalamic Motor Nuclei and Frontal Cortical Areas to the Dorsal Striatum in the Primate

This study examines the organization of VA/VL thalamic inputs to the dorsal “motor” striatum to determine how this afferent projection is organized with respect to corticostriatal afferents from motor, premotor, and cingulate motor areas.

Premotor and parietal cortex: corticocortical connectivity and combinatorial computations.

It appears that this fronto-parietal network functions as a visuomotor controller-one that makes computations based on proprioceptive, visual, gaze, attentional, and other information to produce an output that reflects the selection, preparation, and execution of movements.

Responses of tonically active neurons in the primate's striatum undergo systematic changes during behavioral sensorimotor conditioning

It is concluded that, during the acquisition of a sensorimotor association, TANs widely distributed through the striatum become responsive to sensory stimuli that induce conditioned behavior.

Inferotemporal‐frontal Disconnection: The Uncinate Fascicle and Visual Associative Learning in Monkeys

Animals with uncinate fascicle section showed no impairment in learning to choose between visual stimuli based on their differential association with food reward or other non‐visual cues, but were unable to learn to choose Between visual stimulibased on their different association with another visual stimulus.