Comparison of intravenous penicillin G and oral doxycycline for treatment of Lyme neuroborreliosis.

@article{Karlsson1994ComparisonOI,
  title={Comparison of intravenous penicillin G and oral doxycycline for treatment of Lyme neuroborreliosis.},
  author={Mathias Karlsson and S. Hammers-Berggren and Lars Lindquist and G. T. Stiernstedt and Bo Svenungsson},
  journal={Neurology},
  year={1994},
  volume={44 7},
  pages={1203-7}
}
To compare the efficacy of oral doxycycline and IV penicillin G for the treatment of neuroborreliosis, we randomized consecutive patients with Lyme neuroborreliosis to receive either IV penicillin G (3 g q 6 h) or oral deoxycycline (200 mg q 24 h) for 14 days. All patients had antibodies against Borrelia burgdorferi in serum, CSF, or both, or had a positive CSF culture. Twenty-three patients randomized to penicillin G and 31 patients to doxycycline were included in the study. All patients… CONTINUE READING

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