Comparison of intravenous cocaethylene and cocaine in humans

@article{Hart2000ComparisonOI,
  title={Comparison of intravenous cocaethylene and cocaine in humans},
  author={C. Hart and P. Jatlow and K. Sevarino and E. McCance-Katz},
  journal={Psychopharmacology},
  year={2000},
  volume={149},
  pages={153-162}
}
Abstract Rationale: Cocaethylene is a pharmacologically active homolog and metabolite of cocaine, formed by transesterification of cocaine in the presence of ethanol. Here we relate findings from a randomized, placebo-controlled, double-blind study in which we examined the physiological and subjective effects and pharmacokinetics of IV administered cocaethylene in human volunteers using cocaine as a comparator. Methods: Cocaine-dependent participants randomly received one study drug… Expand
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