Comparison of intraperitoneal antithrombin III and heparin in experimental peritonitis

@article{Akman2008ComparisonOI,
  title={Comparison of intraperitoneal antithrombin III and heparin in experimental peritonitis},
  author={Sema Akman and Mustafa Koyun and Tekinalp Gelen and Mesut Coşkun},
  journal={Pediatric Nephrology},
  year={2008},
  volume={23},
  pages={1327-1330}
}
The antifibrotic effect of heparin, an anticoagulant used routinely in the treatment of peritonitis, is unknown, whereas antithrombin III (AT-III) has both anticoagulant and anti-inflammatory actions. The aim of this study was to compare the antifibrotic and anti-inflammatory effects of AT-III and heparin in rats with experimentally developed peritonitis while on peritoneal dialysis (PD). Sixty-four Wistar albino rats (in four groups of 16) were used in the study. Group 1 received PD solution… CONTINUE READING