Comparison of intracavitary bleomycin and talc for control of pleural effusions secondary to carcinoma of the breast.

@article{Hamed1989ComparisonOI,
  title={Comparison of intracavitary bleomycin and talc for control of pleural effusions secondary to carcinoma of the breast.},
  author={Hisham Hamed and Ian S. Fentiman and Murid A. Chaudary and Robert D. Rubens},
  journal={The British journal of surgery},
  year={1989},
  volume={76 12},
  pages={1266-7}
}
In a prospective randomized study, patients with pleural effusions secondary to breast carcinoma were randomly allocated to be treated by pleurodesis using either intracavitary talc or bleomycin. For 25 assessable treatments in 22 patients, recurrence of effusion was observed in 5 of 15 (33 per cent) of the bleomycin group compared with none in the talc group. It is concluded that talc is superior to bleomycin in controlling pleural effusions secondary to breast carcinoma, but bleomycin may… CONTINUE READING

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