Comparison of intact PTH assay and whole PTH assay in long-term dialysis patients.

@article{Nakanishi2001ComparisonOI,
  title={Comparison of intact PTH assay and whole PTH assay in long-term dialysis patients.},
  author={Shohei Nakanishi and Junichiro James Kazama and Takashi Shigematsu and Yoshiko Iwasaki and Thomas L Cantor and Takeshi Kurosawa and Masafumi Fukagawa},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2001},
  volume={38 4 Suppl 1},
  pages={S172-4}
}
Adynamic bone disease has become a major problem in long-term dialysis patients. It has been suggested that higher levels of parathyroid hormone (PTH) are needed to maintain normal bone turnover in uremia. PTH levels currently are evaluated routinely by intact PTH assay, which may detect inactive 7-84 PTH fragments as well as 1-84 PTH. We examined the efficacy of whole PTH assay, which detects 1-84 PTH exclusively, in 99 nondiabetic patients on maintenance dialysis for more than 10 years… CONTINUE READING