Comparison of insulin degludec/insulin aspart and biphasic insulin aspart 30 in uncontrolled, insulin-treated type 2 diabetes: a phase 3a, randomized, treat-to-target trial.

@article{Fulcher2014ComparisonOI,
  title={Comparison of insulin degludec/insulin aspart and biphasic insulin aspart 30 in uncontrolled, insulin-treated type 2 diabetes: a phase 3a, randomized, treat-to-target trial.},
  author={Gregory R Fulcher and Jens Sandahl Christiansen and Ganapathi Bantwal and Miroslawa Polaszewska-Muszynska and Henriette Mersebach and Thomas Hasseriis Andersen and Leo K. Niskanen},
  journal={Diabetes care},
  year={2014},
  volume={37 8},
  pages={2084-90}
}
OBJECTIVE Insulin degludec/insulin aspart (IDegAsp) is the first combination of a basal insulin with an ultralong duration of action, and a rapid-acting insulin in a single injection. This trial compared IDegAsp with biphasic insulin aspart 30 (BIAsp 30) in adults with type 2 diabetes inadequately controlled with once- or twice-daily (OD or BID) pre- or self-mixed insulin with or without oral antidiabetic drugs. RESEARCH DESIGN AND METHODS In this 26-week, randomized, open-label… CONTINUE READING
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( Abstract )

  • P Kurtzhals, T Heise, HM Strauss
  • 2013

IDegAsp produces dose-proportional glucose-lowering effect in subjects with type 1 diabetes (Abstract)

  • T Heise, L Nosek, O Klein
  • Diabetes 2013;62(Suppl
  • 2013
1 Excerpt

IDegAsp shows distinct prandial and basal glucoselowering effects at steady state in subjects with type 1 diabetes (Abstract)

  • T Heise, L Nosek, H Hastrup
  • Diabetes 2013; 62(Suppl
  • 2013
3 Excerpts

Insulin degludec (IDeg) and insulin aspart (IAsp) can be co-formulated such that the formation of IDeg multi-hexamers and IAsp monomers is retained upon s.c. injection (Abstract)

  • S Havelund, U Ribel, F Hubálek
  • Diabetes 2013;62 (Suppl
  • 2013
2 Excerpts

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