Comparison of incretin immunoassays with or without plasma extraction: Incretin secretion in Japanese patients with type 2 diabetes

@inproceedings{Yabe2012ComparisonOI,
  title={Comparison of incretin immunoassays with or without plasma extraction: Incretin secretion in Japanese patients with type 2 diabetes},
  author={Daisuke Yabe and Koin Watanabe and Kenji Sugawara and Hitoshi Kuwata and Yuka Kitamoto and Kazu Sugizaki and Shuichi Fujiwara and Masahiro Hishizawa and Takanori Hyo and Kyoko Kuwabara and Kayo Yokota and Masahiro Iwasaki and Naomi Kitatani and Takeshi Kurose and Nobuya Inagaki and Yutaka Seino},
  booktitle={Journal of diabetes investigation},
  year={2012}
}
UNLABELLED Aims/Introduction:  The effectiveness of incretin-based therapies in Asian type 2 diabetes requires investigation of the secretion and metabolism of glucose-dependent insulinotropic polypepide (GIP) and glucagon-like peptide 1 (GLP-1). Plasma extractions have been suggested to reduce variability in intact GLP-1 levels among individuals by removing interference that affects immunoassays, although no direct demonstration of this method has been reported. We have evaluated the effects… CONTINUE READING