Comparison of incidence of acute myocardial infarction in patients with type 2 diabetes mellitus following initiation of neutral protamine Hagedorn insulin versus insulin glargine.

@article{Rhoads2009ComparisonOI,
  title={Comparison of incidence of acute myocardial infarction in patients with type 2 diabetes mellitus following initiation of neutral protamine Hagedorn insulin versus insulin glargine.},
  author={George G. Rhoads and Mikhail Kosiborod and Richard W. Nesto and Vivian A. Fonseca and S Lu and Quanwu Zhang and Joanne Micale Foody},
  journal={The American journal of cardiology},
  year={2009},
  volume={104 7},
  pages={910-6}
}
Recent reports have described different risks of acute myocardial infarction (AMI) in association with specific oral antidiabetic medications. The present study compared the AMI incidence rates in new users of traditional neutral protamine Hagedorn (NPH) insulin and a long-acting synthetic insulin analog for basal insulin therapy. We retrospectively examined in-patient medical claims for AMI in a cohort of oral agent-treated patients with type 2 diabetes mellitus after the initiation of basal… CONTINUE READING

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