Comparison of in vitro stability for insulin aspart and insulin glulisine during simulated use in insulin pumps.

@article{Senstius2007ComparisonOI,
  title={Comparison of in vitro stability for insulin aspart and insulin glulisine during simulated use in insulin pumps.},
  author={Jakob Senstius and Christian Keis Poulsen and Aage Hvass},
  journal={Diabetes technology & therapeutics},
  year={2007},
  volume={9 6},
  pages={517-21}
}
BACKGROUND This study was designed to evaluate the stability properties of the marketed insulin aspart (IAsp) and insulin glulisine (IGlu) products during simulated continuous subcutaneous insulin infusion (CSII) for up to 10 days. METHODS Plastic reservoirs containing IGlu or IAsp were placed in MiniMed 508 infusion pumps (MiniMed, Northridge, CA) connected via an infusion set to a collection glass vial. Pumps were shaken continuously (30 oscillations/min, 2 cm amplitude) at 37 +/- 2 degrees… CONTINUE READING
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