Comparison of immune responses and protective efficacy of intranasal prime-boost immunization regimens using adenovirus-based and CpG/HH2 adjuvanted-subunit vaccines against genital Chlamydia muridarum infection.

Abstract

An efficacious Chlamydia vaccine is urgently needed to control Chlamydia infections. Heterologous prime-boost vaccination regimens are emerging as a promising strategy for preventing intracellular viral and bacterial infections. However, it remains to be determined if this regimen would be a feasible and effective approach for Chlamydia infection. In this… (More)
DOI: 10.1016/j.vaccine.2011.10.086

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@article{Brown2012ComparisonOI, title={Comparison of immune responses and protective efficacy of intranasal prime-boost immunization regimens using adenovirus-based and CpG/HH2 adjuvanted-subunit vaccines against genital Chlamydia muridarum infection.}, author={Tyler Brown and Jason W David and Elizabeth Acosta-Ram{\'i}rez and Jessica A. M. Moore and Song Lee and Guangming Zhong and Robert E. W. Hancock and Zhou Xing and Scott Alan Halperin and Jun Wang}, journal={Vaccine}, year={2012}, volume={30 2}, pages={350-60} }