Comparison of human papillomavirus testing strategies for triage of women referred with low-grade cytological abnormalities.

@article{Mesher2013ComparisonOH,
  title={Comparison of human papillomavirus testing strategies for triage of women referred with low-grade cytological abnormalities.},
  author={David Mesher and Anne Szarewski and L. Cadman and Janet Austin and Lesley Ashdown-Barr and Linda Ho and George Terry and Martin P A Young and Mark H. Stoler and Christine O M A Bergeron and Julie McCarthy and Corrina Wright and Stuart Liddle and William Patrick Soutter and Deirdre Lyons and Jack Cuzick},
  journal={European journal of cancer},
  year={2013},
  volume={49 9},
  pages={2179-86}
}
AIM To compare triage strategies using different human papillomavirus (HPV) consensus and genotyping tests and a p16(INK4a) test. METHODS 1228 women referred with a borderline or single mildly dyskaryotic smear. Samples were taken at colposcopy using PreservCyt. Tests included Hybrid Capture 2, Abbott RealTime PCR, BD HPV, Cobas 4800, PreTect HPV-Proofer, APTIMA and p16(INK4a). Results were based on the worst histology within 9 months. RESULTS 97/1228 (7.9%) women had CIN3+ (203/1228 (17… CONTINUE READING

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