Comparison of human gut microbiota in control subjects and patients with colorectal carcinoma in adenoma: Terminal restriction fragment length polymorphism and next-generation sequencing analyses.

@article{Kasai2016ComparisonOH,
  title={Comparison of human gut microbiota in control subjects and patients with colorectal carcinoma in adenoma: Terminal restriction fragment length polymorphism and next-generation sequencing analyses.},
  author={Chika Kasai and Kazushi Sugimoto and Isao Moritani and Junichiro Tanaka and Yumi Oya and Hidekazu Inoue and Masahiko Tameda and Katsuya Shiraki and Masaaki Ito and Yoshiyuki Takei and Kojiro Takase},
  journal={Oncology reports},
  year={2016},
  volume={35 1},
  pages={
          325-33
        }
}
Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in Japan. The etiology of CRC has been linked to numerous factors including genetic mutation, diet, life style, inflammation, and recently, the gut microbiota. However, CRC-associated gut microbiota is still largely unexamined. This study used terminal restriction fragment length polymorphism (T-RFLP) and next-generation sequencing (NGS) to analyze and compare gut microbiota of Japanese control subjects and Japanese… CONTINUE READING

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