Comparison of human B cell activation by TLR7 and TLR9 agonists

Abstract

Human B cells and plasmacytoid dendritic cells (pDC) are the only cells known to express both TLR7 and TLR9. Plasmacytoid dendritic cells are the primary IFN-α producing cells in response to TLR7 and TLR9 agonists. The direct effects of TLR7 stimulation on human B cells is less understood. The objective of this study was to compare the effects of TLR7 and… (More)
DOI: 10.1186/1471-2172-9-39

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@article{Hanten2007ComparisonOH, title={Comparison of human B cell activation by TLR7 and TLR9 agonists}, author={John A Hanten and John P. Vasilakos and Christie L Riter and Lori Neys and Kenneth E Lipson and Sefik S. Alkan and Woubalem Birmachu}, journal={BMC Immunology}, year={2007}, volume={9}, pages={39 - 39} }