Comparison of high-dose CY and growth factor with growth factor alone for mobilization of stem cells for transplantation in patients with multiple myeloma

@article{Gertz2009ComparisonOH,
  title={Comparison of high-dose CY and growth factor with growth factor alone for mobilization of stem cells for transplantation in patients with multiple myeloma},
  author={Morie A Gertz and Shaji K Kumar and Martha Q. Lacy and Angela Dispenzieri and Suzanne R. Hayman and Francis K Buadi and David Dingli and Dennis A Gastineau and Jeffrey L Winters and Mark R Litzow},
  journal={Bone Marrow Transplantation},
  year={2009},
  volume={43},
  pages={619-625}
}
We retrospectively analyzed outcomes of 716 patients with multiple myeloma who were mobilized using CY and growth factor (n=370) or growth factor alone (n=346) before SCT. Patients receiving CY had higher stem cell yields than the growth factor only group (median number of apheresis sessions needed to achieve stem cell collection goals, two vs four sessions, respectively (P=0.001)). However, patients treated with CY required more time for engraftment of platelets and neutrophils (P<0.001 for… CONTINUE READING

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