Comparison of high-dimensional confounder summary scores in comparative studies of newly marketed medications.

Abstract

OBJECTIVE To compare confounding adjustment by high-dimensional propensity scores (hdPSs) and historically developed high-dimensional disease risk scores (hdDRSs) in three comparative study examples of newly marketed medications: (1) dabigatran vs. warfarin on major hemorrhage; (2) on death; and (3) cyclooxygenase-2 inhibitors vs. nonselective nonsteroidal… (More)
DOI: 10.1016/j.jclinepi.2016.02.011

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