Comparison of hemodialysis versus hemoperfusion in the clearance of high-dose methotrexate in pigs.

Abstract

To evaluate the different capabilities of hemo-perfusion (HP) and hemodialysis (HD) treatment in resolving the side effects during high-dose methotrexate (MTX) therapy, an experimental comparative study was done. Under general anesthesia, 12 female Large-White pigs, 35 +/- 5 kg body weight, underwent a bilateral renal vessel ligature to create an acute… (More)

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@article{Giardino1995ComparisonOH, title={Comparison of hemodialysis versus hemoperfusion in the clearance of high-dose methotrexate in pigs.}, author={Richard Giardino and Mary Elizabeth Fini and Gianluca Giavaresi and Michele Spighi and Stefano Faenza and Matteo Florio and Marco Orlandi and Siergio Stefoni}, journal={Artificial organs}, year={1995}, volume={19 4}, pages={362-5} }