Comparison of glutamate-evoked pain between the temporalis and masseter muscles in men and women.

@article{Castrillon2012ComparisonOG,
  title={Comparison of glutamate-evoked pain between the temporalis and masseter muscles in men and women.},
  author={Eduardo Castrillon and Brian Edwin Cairns and Kelun Wang and Lars Arendt-Nielsen and Peter Svensson},
  journal={Pain},
  year={2012},
  volume={153 4},
  pages={823-9}
}
Pain in myofascial temporomandibular disorder (TMD) can affect both the masseter and temporalis muscles. Glutamate injection into the masseter muscle evokes pain that is greater in men than in women and this pain is attenuated by co-injection of the N-methyl-d-aspartate (NMDA) receptor antagonist ketamine (10 mmol/L) in men. Animal studies suggested that pain induced by peripheral NMDA receptor activation could differ between the temporalis and masseter muscles and between men and women. The… CONTINUE READING
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