Comparison of glucocorticoid and cysteinyl leukotriene receptor antagonist treatments in an experimental model of chronic airway inflammation in guinea-pigs.

@article{LeickMaldonado2004ComparisonOG,
  title={Comparison of glucocorticoid and cysteinyl leukotriene receptor antagonist treatments in an experimental model of chronic airway inflammation in guinea-pigs.},
  author={Edna A. Leick-Maldonado and Fernando Uliana Kay and Marcos de Camargo Leonhardt and David Itiro Kasahara and Carla M{\'a}ximo Prado and Fl{\'a}vio Tavares Fernandes and Marco Aur{\'e}lio Martins and Iolanda Calvo Tib{\'e}rio},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={2004},
  volume={34 1},
  pages={
          145-52
        }
}
BACKGROUND Leukotriene receptor antagonists have been demonstrated in several studies to possess bronchodilating and anti-inflammatory properties in asthma. However, there are few experimental studies performed to compare the effects of anti-leukotrienes and glucocorticoids, most used anti-inflammatory agents in asthma. In the present study, we evaluated the effects of treatment with dexamethasone or montelukast on eosinophil and mononuclear cell recruitment in an experimental model of allergen… CONTINUE READING

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